This paper discusses the design of the information management system of traditional Chinese medicine hospitals based on cloud computing technology. Aiming at the challenges faced by the information construction of traditional Chinese medicine hospitals, a solution that integrates cloud computing, big data, artificial intelligence and other technologies is proposed. The system includes four core modules of electronic medical record management, appointment registration management, drug management and health management, and uses a micro-service structure to realize the decoupling and collaboration between the modules. Finally, the performance and scalability of the system are comprehensively evaluated through experiments. The experimental results show that the system performs well in terms of high concurrent processing capacity， data throughput and elastic scalability， providing a reliable technical solution for the informatization construction of traditional Chinese medicine hospitals.